The Digital Imaging and Graphics (DIG) Group in the CUNY PhD Program In Computer Science is holding a seminar jointly with the New York Topology Seminar on Friday, April 11, from 3:30 pm to 5:30 pm in the Computer Science Thesis Room (Room 4421 at the Graduate Center).
3:30 – 4:00: Tea and informal discussions.
4:00 – 5:00: Presentation by Lucas Oliviera, PhD Program in Computer Science
Title: Using a Topological Descriptor to Investigate Structures of Virus Particles.
Abstract: An understanding of the three-dimensional structure of a biological macromolecular complex is essential to fully understand its function. A component tree is a topological and geometric image descriptor that captures information regarding the structure of an image based on the connected components determined by different grayness thresholds. We believe interactive visual exploration of component trees of (the density maps of) macromolecular complexes can yield much information about their structure. To illustrate how component trees can convey important structural information, we consider component trees of four recombinant mutants of the procapsid of a bacteriophage (cystovirus phi6), and show how differences between the component trees reﬂect the fact that each non-wild-type mutant of the procapsid has an incomplete set of constituent proteins.
5:00 – 5:30: Questions and informal discussions.